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Vetoquinol Zylkene 75-mg Capsules Calming Supplement for Small Dogs & Cats

Vetoquinol Zylkene 75-mg Capsules Calming Supplement for Small Dogs & Cats

By Vetoquinol 8 reviews analyzed Updated Nov 2025 85% confidence
6.8 /10
Quality
7.0
Value
6.5
Design
7.0
Function
7.5
Durability
6.5

In a Nutshell

  • Effective in reducing pet anxiety
  • Can be difficult to administer due to large capsule size
  • Some pets may refuse altered food
  • Generally well-received by users

Quick Verdict

Vetoquinol Zylkene works well for calming anxious pets but can be challenging to administer.

Quick Stats

Reviews Analyzed 8
Would Recommend 88%
Would Buy Again 63%
Avg Lifespan Not specified

Pet Compatibility

🐕 Dogs
Suitable
🐈 Cats
Suitable

Pros & Cons

Pros

  • Effective Calming (5)

    Helps pets become more calm and relaxed.

  • Quick Results (3)

    Noticeable effects within a short period.

  • Reduces Litter Box Issues (2)

    Helps in reducing litter box accidents.

  • Easy to Use (2)

    Can be given to pets easily.

  • Works with Other Medications (1)

    Can be used in conjunction with other medications.

Cons

  • Large Capsule Size (3) major

    Capsules are too large for some pets to eat directly.

    Tip: Open the capsules and mix the contents into wet food.

  • Picky Eaters (2) major

    Some pets refuse to eat the food mixed with the supplement.

  • Ineffective for Some Pets (2) medium

    Does not work for all pets.

Who Is This For?

Best For

  • Pet owners with anxious pets — Effective in reducing anxiety and calming pets.
  • Owners of small dogs and cats — Suitable for small pets.

Skip If

  • Owners of picky eaters — Some pets may refuse food mixed with the supplement.
  • Those looking for an easy-to-administer solution — Capsules are large and need to be mixed with food.

Durability & Care

Expected Lifespan Not specified

Rating Distribution

4.6
8 reviews
5★
63%
4★
25%
3★
0%
2★
13%
1★
0%
effective calming (5) quick results (3) large capsule size (3) picky eaters (2)

Common Questions

How effective is Vetoquinol Zylkene for anxious pets?

Vetoquinol Zylkene is generally effective in calming anxious pets, particularly cats. It helps reduce anxiety and litter box issues. However, the large capsule size can be a challenge for administration and may not work for all pets.

Can Vetoquinol Zylkene be used with other medications?

Yes, Vetoquinol Zylkene can be used in conjunction with other medications like gabapentin and Fluoxetine. It seems to have a fast and noticeable effect when combined with these medications.

What should I do if my pet refuses to eat the food mixed with Vetoquinol Zylkene?

If your pet refuses the food mixed with Vetoquinol Zylkene, you can try mixing the capsule powder into a churu or another pet treat that your pet enjoys.

Highlighted Reviews

— Kelly

"This has helped two of my cats. They act more calm when I give it to them. The only downside is that the capsule is too big to give a cat and I don't think they would eat it mixed in their food since it has a taste. I've been emptying each capsule into two of the size 3 capsules and placing it in..."

— Aleksandra

"I got these for our 3 year old boy who is very skittish and anxious. I’ve been looking around at calming supplements for him because I want to find something that will help him before we have to turn to Fluoexetine which his vet has already prescribed. We also have Feliway diffusers so I thought w..."

Bottom Line

Recommended for pet owners looking to calm anxious pets, but be prepared for potential difficulty in administering the capsules.

6.8 /10
Good